The Next Generation of Fermented Wheat Germ Extract (FWGE)

Metatrol: It’s the FWGE for everyone!

  • The most potent Fermented Wheat Germ Extract (FWGE) dietary supplement ever produced.
  • The only FWGE that’s gluten-free!
  • Just two easy-to-take capsules are equal to 5.5 g of AveUltra®.
  • Okay to take any time of day.

Since it was first introduced in the United States in 2005, Fermented Wheat Germ Extract (FWGE) has been amazing researchers, impressing doctors, and satisfying consumers. Now, the most potent and super-concentrated form of FWGE is available, and research shows that it’s better than ever!

American BioSciences developed the patent-pending technology to concentrate FWGE so that non-active molecules, including gluten, are excluded. Studies show that 41 mg of FWGE super-concentrate (FWGE-SC™), has the same biological effect as 5,500 mg of whole FWGE.

Everything you want and need in FWGE, nothing you don’t!

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Product Description

A Miracle of Nature for you. Impressive research for your doctor.

Metatrol  is the “next generation of Fermented Wheat Germ Extract (FWGE)”; the most potent and super-concentrated FWGE in just two gluten-free capsules.

More than 40 research articles have been published in peer-reviewed medical journals describing FWGE’s efficacy and remarkable health benefits in a wide range of serious health challenges*.

Research shows that FWGE helps to:

  • Redirect energy to healthy cells for renewed vitality, well-being, and enhanced quality of life.*
  • Support optimal immune system function.*
  • Promote cell metabolic regulation.*
  • Maintain healthy appetite, weight, and cell mass.*

Although these sound like benefits only a doctor can appreciate, they are benefits you can actually feel!* Imagine your immune system working at peak performance, with enhanced energy, quality of life, a healthy appetite, and overall well-being of the body, mind, and spirit.*

Try these super-concentrated, powerful Metatrol capsules to help keep your immune system strong, so that you can fight back!*

What is Fermented Wheat Germ Extract (FWGE)?

Met-Figure-1A Marvel of Science!

Medical researchers have long known that stress and injury can alter cellular metabolism and weaken immune system regulation, leading to serious health complications. Nobel Laureate, Dr. Albert Szent-Gyorgyi, published research in the 1980s showing that compounds found in very minute quantities in wheat germ could help restore healthy cellular metabolic function.* Fermented Wheat Germ Extract (FWGE) was created when a process was developed to concentrate these compounds by fermenting wheat germ with baker’s yeast.

A Miracle of Nature!

American BioSciences first introduced FWGE to the United States in 2005, and it’s been amazing researchers, impressing doctors, and satisfying consumers ever since. More than 40 articles have been published in peer-reviewed medical journals describing hundreds of studies with FWGE in cell lines, in animals, and in human clinical trials showing safety and efficacy. Research shows that FWGE helps to provide remarkable health benefits for a wide range of serious health challenges.*

Why is Metatrol the next generation of FWGE and how is it different from AvéULTRA® or other FWGE products?

The “BioActive Fraction”

Extensive research on FWGE drew the attention of scientists at a leading NCI-designated academic research center. They invited American BioSciences to join a research collaboration to identify the individual molecules in FWGE that account for its biological activity, and find the “bioactive fraction”. This research collaboration determined:

  • In its natural form, FWGE consists of thousands of molecules, but 100 percent of the biological activity and health benefits are provided by less than 100 molecules which compose the “bioactive fraction.”
  • Non-active molecules dilute FWGE bioactives, and they include gluten and gliadin, which may contribute to unwanted inflammation.

American BioSciences developed a patent-pending combination of technologies used in food processing, which concentrates the“bioactive fraction,” referred to as Fermented Wheat Germ Extract–Super Concentrate (FWGE-SC). Non-active molecules, including gluten, are excluded. Studies show that 41 mg of FWGE-SC, found in Metatrol, has the same biological effect as 5,500 mg of pure FWGE, found in AvéULTRA, and 17,000 mg of spray dried FWGE, found in original Avé®. (Fig. 1)


As a dietary supplement for adults, take two Metatrol capsules per day (before, during or after meals, as preferred). For people weighing over 200 lbs, take four capsules per day.

Caution: KEEP OUT OF REACH OF CHILDREN. Should not be taken during pregnancy or while nursing. Consult with a healthcare professional for recommended usage levels for children and guidance using more than four capsules per day. Do not consume Metatrol if you are taking immune suppressive medication. This product is manufactured with wheat germ and baker’s yeast. Use cautiously if sensitive to these ingredients. Gluten and gliadin are removed, so that this product is gluten-free.

This product is vegetarian.

This product is not intended to be the sole source of nutrients in the diet. This product is not affected by temperatures under 122° F (50° C). Best if stored in a dry place at temperatures less than 80° F (26 °C).

Click here for Fermented Wheat Germ Extract (FWGE) Published Research

"I have been taking Metatrol for about 12 days now and I have to say that I really feel a difference. I suffer with terrible joint discomfort and had a stroke about 4 years ago. Since taking Metatrol, I feel better and have more energy than I used to. I am a firm believer in natural products. Thank you for this product."

David B., Pennsylvania

"I was diagnosed with a serious health challenge. A friend of mine told me about a product called AvéULTRA. This product was designed to boost and support the immune system. I ordered the product and started taking right away. I noticed benefits immediately. I recuperated very quickly from the surgery; I had a healthy appetite and noticeable energy. I believe that this product has helped me tremendously. I feel good!

In July of 2015, I was introduced to a new product called Metatrol. I have been taking Metatrol for almost 6 months now and I can honestly say that I love this product! I feel the same effects that I experienced with AvéULTRA, but with many additional benefits. I love the convenience of this product. I can take it any time of day, with or without food. I don't have to worry about mixing and stirring. I no longer have to refrigerate.

The 2 capsules are so convenient – I never forget to take them. I place them beside my bed and they are the last thing I do before I go to sleep. I am so thrilled and thankful for this product and look forward to many years of good health."

Mary Ann O., New York

"I had read about Metatrol in the February 2016 issue of Dr. David Williams’ Alternatives newsletter. I started taking Metatrol after my surgery, and took it for two months before going back for follow up tests. When I went back my tests were clear. I told my doctors that I was taking Metatrol, and I had to explain what it was as they had not heard of it before. I gave them information about the product and what it does.

I have told many people about Metatrol. I recently bought some for my friend who is ill and I hope it will be as successful for her as it was for me."

Harvey H., New York

"I have to say that I am improving every day. I am now taking Metatrol. This product is excellent- so convenient – no more mixing and stirring, convenience of being able to take any time of day and no need to worry about refrigeration! I love this product."

Theresa B., New Jersey

Customer Satisfaction Guarantee 90-Day Risk-Free Trial

*Orders placed AFTER 12:00 pm EST will ship the next business day

You will be thrilled with how well these supplements work. But in the unlikely event you wish to return your purchase, simply call our Customer Service department at 1-866-298-9944 within 90 days of purchase. We promise to rush you a full refund of the product cost, no questions asked.


Shipping and Handling United States Addresses

Standard Delivery

5-10 Business Days
$9.95For Non AvéULTRA Shipments
$16.95For Orders including AvéULTRA

Next Day Delivery

1 Business Day
$27.95For Order Under $250.00
$20.00For Orders Over $250.00

Free SHipping

Shipping and Handling International

No delivery time can be guaranteed, but 3-10 business days can be reasonably expected.


$35.00For Non AvéULTRA Shipments
$50.00For Orders including AvéULTRA

All Other International Shipments

$45.00For Non AvéULTRA Shipments
$65.00For Orders including AvéULTRA


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